I-TASSER是一款用於預測蛋白質結構和功能的工具，網站鏈接：https://zhanglab.ccmb.med.umich.edu/I-TASSER/
具體描述如下：
I-TASSER (Iterative Threading ASSEmbly Refinement) is a hierarchical approach to protein structure and function prediction. It first identifies structural templates from the PDB by multiple threading approach LOMETS, with full-length atomic models constructed by iterative template fragment assembly simulations. Function insights of the target are then derived by threading the 3D models through protein function database BioLiP. I-TASSER (as 'Zhang-Server') was ranked as the No 1 server for protein structure prediction in recent community-wide CASP7, CASP8, CASP9, CASP10, CASP11, and CASP12 experiments. It was also ranked as the best for function prediction in CASP9. The server is in active development with the goal to provide the most accurate structural and function predictions using state-of-the-art algorithms. Please report problems and questions at I-TASSER message board and our developers will answer the questions.
使用步驟很簡單，先把要預測的蛋白質的氨基酸序列黏貼在框框里，如下圖紅色框框所示：
填寫郵箱，密碼（如果之前沒注冊過的話，需要點擊password那欄的here進行注冊，注冊完郵箱會發送密碼），ID可以隨意寫，最后，點擊“Run I-TASSER”。1~2天郵件會收到結果通知。
