有時候我們想畫出所有SNP的LD關系圖,則需要在命令行添加“-skipcheck”命令行,如下所示:
java -jar Haploview.jar -skipcheck -n -pedfile 800kb1.ped -info 800kb1.info -png -out 800kb
這樣就不需要經過haploview的過濾標准了。
如果只想過濾某個標准,則可參看下來參數
-skipcheck Skip all the genotype data quality checks and uses all markers for all analyses. -minMAF <threshold> Exclude all markers with minor allele frequency below <threshold>, which must be between 0 and 0.5. Default of 0. This option works in GUI mode. -maxMendel <integer> Exclude markers with greater than <integer> Mendelian inheritance errors. Default of 1. This option works in GUI mode. -minGeno <threshold> Exclude markers with less than <threshold> fraction of nonzero genotypes. <threshold> must be between 0 and 1 with a default of 0.5. This option works in GUI mode. -hwcutoff <threshold> Exclude markers with a Hardy Weinberg p-value less than <threshold>, which ranges from 0 to 1 with a default of 0.001 This option works in GUI mode. -maxDistance <distance> Maximum intermarker distance for LD comparisons (in kilobases). Default is 500. This option works in GUI mode. -missingCutoff <threshold> Exclude individuals with more than <threshold> fraction missing data, where <threshold> is a value between 0 and 1 with a default of 0.5. This option works in GUI mode.