Seurat | 單細胞分析工具


Seurat是一個老牌的單細胞分析工具了(satija的力作),我之前測試過,但是沒怎么用。

最近發現這個工具又publish在了NBT上,所以很有必要看一下這篇文章。

 

Integrating single-cell transcriptomic data across different conditions, technologies, and species

主要目的:identifying subpopulations of cells that are present across multiple data sets

主要就是為了多樣品之間的比較,甚至不同物種間的對比。

 

Overview of Seurat alignment workflow
We aimed to develop a diverse integration strategy that could compare scRNA-seq data sets across different conditions, technologies, or species.

 

Identifying shared correlation structures across data sets

Machine-learning techniques for ‘data fusion’ aim to integrate information from multiple experiments into a consistent representation.

 

待續~


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